Bicillin L-A shortage (syphilis treatment)

Due to a national shortage of Bicillin L-A (Benzathine Penicillin G), used to ensure safe and effective syphilis treatment, interim clinical direction applies until supply stabilizes.

Bicillin L-A, will be prioritized for:

• Pregnant cases and pregnant contacts of cases, and
• Cases and contacts likely to be lost to follow-up

Recommended treatment of all other adult cases of:

• Infectious syphilis is Doxycycline 100 mg PO BID x 14 day
• Late latent syphilis is Doxycycline 100 mg PO BID x 28 days

Due to limited supply:

• Peripheral and community clinics will receive smaller allocations of Bicillin L-A, and
• Clinics are asked to place small, incremental orders to avoid stock-outs

For patient treatment history, case consultation or to order Bicillin L-A, contact STI Centralized Services at 1-855-945-6700 (option 4).